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The Mutation Jacket is used to protect the solider a.k.a the player from one attack from the mutant (zombie), and also gives the mutants extra armor points (1000 normal , 1100 if normal armor is equipped). Basically the armor is 1 time only so if the mutants respawned the armor points won't regenerated.
It's also available in M60-Adv crates.
In the normal hero mode , the Hero comes already with a mutation jacket.